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The Beta Cell in Its Cluster: Stochastic Graphs of Beta ~ The Beta Cell in Its Cluster: Stochastic Graphs of Beta Cell Connectivity in the Islets of Langerhans. Deborah A. Striegel, 1 Manami Hara, 2 and Vipul Periwal 1 , * Morten Gram Pedersen, Editor
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The Beta Cell in Its Cluster: Stochastic Graphs of Beta ~ Pancreatic islets of Langerhans consist of endocrine cells, primarily α, β and δ cells, which secrete glucagon, insulin, and somatostatin, respectively, to regulate plasma glucose. β cells form irregular locally connected clusters within islets that act in concert to secrete insulin upon glucose stimulation.
Cale N Street's research works / University of Alberta ~ Reference: The Beta Cell in Its Cluster: Stochastic Graphs of Beta Cell Connectivity in the Islets of Langerhans Heterogenous expression of nestin in human pancreatic tissue precludes its use as .
Prognostic Value of Graph Theory-Based Tissue Architecture ~ Download PDF. Published: 01 . The Beta Cell in Its Cluster: Stochastic Graphs of Beta Cell Connectivity in the Islets of Langerhans Deborah A. Striegel, Manami Hara .
Lisa M. H. Helms's research works / University of Alberta ~ Reference: The Beta Cell in Its Cluster: Stochastic Graphs of Beta Cell Connectivity in the Islets of Langerhans Heterogenous expression of nestin in human pancreatic tissue precludes its use as .
Manami Hara's research works / University of Chicago, IL ~ Download full-text. . The Beta Cell in Its Cluster: Stochastic Graphs of Beta Cell Connectivity in the Islets of Langerhans. . and d cells are clustered to form islets of Langerhans, the .
Stereological analyses of the whole human pancreas ~ The Beta Cell in Its Cluster: Stochastic Graphs of Beta Cell Connectivity in the Islets of Langerhans. PLoS Comput. . Download references.
Clusters of Conserved Beta Cell Marker Genes for ~ Distribution of conserved beta cell marker genes over three clusters with different tissue selectivity. The 332 beta cell marker genes were visualized for their natural tissue tropism in the context of the Human Gene Atlas , a public repository of mRNA expression profiles of human organs or cell types.Beta cell-selectivity was independently confirmed for most markers (Figure 2).
Human beta cell mass and function in diabetes: Recent ~ The current literature suggests that beta cell mass and function contribute in different ways to the development of T1D and T2D ().In T1D (Figure 1A), the prediabetic phase seems to be characterized by a prolonged, gradual, functional impairment followed by a rapid decline in beta cell mass just before the onset of hyperglycemia.The amount of mass reduction at clinical manifestation is .
What happens to Beta-cells in Type 2 Diabetes? - MedClique ~ Beta cell loss exceeds new beta cell production or cell proliferation in the progression of type 2 diabetes. Furthermore, there is secretion and extracellular deposition of the protein amyloid in the islets of the pancreas. Amylin is the peptide that makes up these deposits is normally co-secreted with insulin by beta cells. With progression .
Adaptation of pancreatic islet cyto-architecture during ~ The Beta Cell in Its Cluster: Stochastic Graphs of Beta Cell Connectivity in the Islets of Langerhan. August 2015 · PLoS Computational Biology Deborah A Striegel
Beta cells gene expression markers / PanglaoDB ~ SRA SRS tissue cluster cell type p-value FDR View; SRA701877: SRS3279684: Pancreatic islets: 0: Beta cells: 6.81E-12: 8.38E-9: view data: SRA701877: SRS3279694 .
Beta cell / biology / Britannica ~ The islets of Langerhans contain alpha, beta, and delta cells that produce glucagon, insulin, and somatostatin, respectively. A fourth type of islet cell, the F (or PP) cell, is located at the periphery of the islets and secretes pancreatic polypeptide. These hormones regulate one another's secretion through paracrine cell-cell interactions.
Clinical Islet Isolation / SpringerLink ~ Striegel DA, Hara M, Periwal V. The beta cell in its cluster: stochastic graphs of beta cell connectivity in the Islets of Langerhans. PLoS Comput Biol. 2015;11(8):e1004423. PubMed CrossRef PubMedCentral Google Scholar
Bacterial assembly in the bio-cake of membrane bioreactors ~ There were distinct patterns in the beta-diversity dynamics of the bio-cake on membranes under different fluxes and fouling stages. Two complementary nonparametric analyses (Adonis and analysis of similarity) also supported the above findings . 3.3. Deterministic vs. stochastic processes in guiding bio-cake community assembly
Carboxybetaine-modified succinylated chitosan-based beads ~ Pancreatic islets, also known as Langerhans islets, are spherical units that are comprised of clusters of cells distributed throughout the pancreas [].The β-cells are one of the major cell types within islets and are involved in storing and releasing insulin, a hormone that is critical in the regulation of blood glucose levels []. β-cell activities are tightly controlled by neighbouring .
Beta-Cell Function and Failure / IntechOpen ~ Beta cells are a type of cell in the pancreas located in the so-called islets of Langerhans. They make up 65-80% of the cells in the islets. The Islets diameter is about 50 to 300 micrometers. They are composed of several types of cells. At least 70 percent are beta cells, which are localized in the core of the islet.
Maturation of Stem Cell-Derived Beta-cells Guided by the ~ 2. Pancreas ontogeny. The pancreas is a glandular organ whose endocrine cells are organized in small clusters, the islets. The two main endocrine cell types that make up the islets are the insulin-producing beta-cells and the glucagon-producing alpha-cells, whose tightly coordinated and opposing actions are essential for the maintenance of normoglycemia.
Synchronization and Critical Behavior in Beta-Cell ~ The pancreatic islets of Langerhans' are multicellular micro-organs which are integral to maintaining glucose homeostasis through secretion of insulin. Beta cells within islets synchronize their insulin release through cell-cell communication to create large bursts to meet physiological needs.
What is the definition of beta cell? - WebMD ~ A beta cell is a type of cell in an area of the pancreas called the islets of Langerhans. Beta cells make and release insulin, which helps control the glucose level in the blood.
11. Graph-Based Clustering Algorithms / Data Clustering ~ A link-based clustering algorithm can also be considered as a graph-based one, because we can think of the links between data points as links between the graph nodes. 11.1 Chameleon. The chameleon (Karypis et al., 1999) algorithm is a graph-based clustering algorithm.
Beta cell - Wikipedia ~ Beta cells (β cells) are a type of cell found in pancreatic islets that synthesize and secrete insulin and amylin.Beta cells make up 50–70% of the cells in human islets. In patients with Type I Diabetes, beta-cell mass and function are diminished, leading to insufficient insulin secretion and hyperglycemia.
Imaging Beta Cell Regeneration and Interactions with Islet ~ We observed GFP only in beta cells that were either organized in large multiple islets (Fig. 1a, dashed line) or in smaller, caudal islets or individual beta cells (Fig. 1a, bracket). Fluorescence within the entire endocrine pancreas is shown in Figure 1b. A 0.4 mm volume of clustered, large multiple islets located anteriorly is followed by a .