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The CAPRISA Clinical Trials: HIV Treatment and Prevention ~ The book concludes with a chapter about the challenges facing future HIV prevention and treatment trials. The CAPRISA Clinical Trials: HIV Treatment and Prevention is a resource for undergraduate and postgraduate students, health care providers, doctors, decision-makers and researchers who are seeking guidance and insights on clinical trials .

The CAPRISA Clinical Trials: HIV Treatment and Prevention ~ Since its inception 14 years ago, CAPRISA has conducted numerous clinical studies that have influenced international TB-HIV treatment guidelines as well as HIV prevention through innovations in the microbicide and vaccine fields. This book provides a historical account of how each of CAPRISA's high impact studies was created, developed, implemented, analysed and communicated. In doing so, the .

HIV and TB Treatment / CAPRISA ~ CAPRISA TB HIV clinical trials completed or ongoing CAPRISA led the way in introducing integrated antiretroviral therapy (ART) and TB treatment for co-infected patients. The CAPRISA 001 NIH funded START study demonstrated the pharmacokinetic interactions of Rifampicin - the backbone of TB therapy, and Efavirenz, the non-nucleoside reverse .

Clinical Trials of Broadly Neutralizing Monoclonal ~ The Centre for the AIDS Programme of Research in South Africa (CAPRISA) 012 trial is supported by the European and Developing Countries Clinical Trials Partnership (grant RIA2017S) and the South African Medical Research Council’s Special Initiative on HIV Prevention Technology.

HIVinfo / Information on HIV/AIDS Treatment, Prevention ~ Select Join a Clinical Trial for information on HIV-related clinical trials conducted at various NIH Institutes and Centers and how to get involved. AIDSource - HIV Navigation Resources Find links to resources about HIV navigation, retention in care, and tools for navigators.

eThekwini CAPRISA Research Clinic - HIV Vaccine Trials Network ~ The Centre for the AIDS Programme of Research in South Africa(CAPRISA) conducts research that is globally relevant and locally responsive, contributing to understanding HIV pathogenesis, prevention and epidemiology as well as the links between tuberculosis and AIDS care.

Vaccine and Pathogenesis / CAPRISA ~ CAPRISA is responding to this challenge through support of HIV Vaccine Trials Network studies, and laboratory research to inform vaccine design. The pivotal study in this research programme is the CAPRISA 002 Acute Infection study which aims to characterize the viral set point and clinical progression in subtype C infection and identify host .

Research Toward a Cure Trials – Treatment Action Group ~ Download this chart as a PDF. A listing of clinical trials and observational studies related to the research effort to cure HIV infection, mainly derived from the clinicaltrials.gov online registry. Click the trial registry identifier numbers for a link to the full entry containing detailed information on the trial design, enrollment criteria, principal investigators and location(s).

Rolling Out of Tenofovir Gel in Family Planning Clinics ~ CAPRISA 008 was a two-arm, open-label, randomised controlled, non-inferiority implementation trial, which provided participants from CAPRISA 004 with post-trial access to tenofovir gel while generating evidence that could be used for future implementation of topical PrEP (tenofovir gel) in women.

Current ethical issues in HIV/AIDS research and HIV/AIDS ~ Introduction. HIV/AIDS has claimed more deaths worldwide (WHO). With the highest percentage of people with HIV/AIDS living in sub‐Saharan Africa, South Africa has been named the epicentre of HIV/AIDS (Health Systems Trust).The advent of antiretroviral (ARV) treatment even with its limitations to slow the progression of the disease rather than cure has prolonged the life of affected individuals.

Salim Abdool Karim / Columbia Public Health ~ Salim S. Abdool Karim is a clinical infectious diseases epidemiologist who is widely recognised for his research contributions in HIV prevention and treatment. He is CAPRISA Professor for Global Health in the Department of Epidemiology at the Mailman School of Public Health at Columbia University. He is also Director of the Centre for the AIDS Program of Research in South Africa (CAPRISA), Pro .

CAPRISA 003: Timing of Antiretroviral Initiation in HIV-TB ~ In the SAPiT trial, 642 HIV-TB coinfected patients were randomized to 3 arms: receiving ART within 4 weeks of starting TB treatment (early treatment arm; Arm-1), after the intensive phase of TB .

AIDSinfo Drug Database - Apps on Google Play ~ The AIDSinfo HIV/AIDS Drug Database app provides mobile access to information about drugs approved to treat HIV infection, drugs that are used to treat other infections or diseases common to people living with HIV, and also HIV/AIDS-related drugs that are being studied in clinical trials. This app is provided free from the National Library of Medicine at the National Institutes of Health.

Trial participation disclosure and gel use behavior in the ~ Study population. This study was conducted simultaneously with the CAPRISA 004 microbicide gel clinical trial in KwaZulu-Natal, South Africa. Participants (n = 277) were recruited from the CAPRISA 004 study population (n = 889).All trial participants with a positive HIV test result at their monthly clinic visit were targeted for recruitment 1 and 72 confirmed positive were enrolled.

Design challenges facing clinical trials of the ~ Design challenges facing clinical trials of the effectiveness of new HIV prevention technologies Anneke C. GROBLER , MSc 1 and Salim S. ABDOOL KARIM , MB ChB, PhD 1, 2 1 Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, South Africa,

Quarraisha Abdool Karim - Wikipedia ~ Additionally, at the XVIII International AIDS Conference, 2010, the results of their CAPRISA 004 study led to a standing ovation, an uncommon occurrence at a scientific meeting. In 2017, with other leaders from the project, Abdool Karim edited The CAPRISA Clinical Trials: HIV Treatment and Prevention.

AIDSinfo HIV/AIDS Guidelines - Apps on Google Play ~ The AIDSinfo HIV/AIDS Guidelines app provides mobile access to the federally approved HIV/AIDS medical practice guidelines. These clinical guidelines offer recommendations approved by expert panels for the treatment of adult, adolescent, pediatric, and perinatal HIV infection, as well as recommendations for the treatment of HIV-related opportunistic infections in adults, adolescents, and children.

CONRAD (organization) - Wikipedia ~ CONRAD (Contraception Research and Development) is a non-profit organization scientific research organization that works to improve the reproductive health of women, especially in developing countries.CONRAD was established in 1986 under a cooperative agreement between Eastern Virginia Medical School (EVMS) and the United States Agency for International Development(USAID).

CAPRISA 004 - an overview / ScienceDirect Topics ~ In 2010, results from CAPRISA 004, the first clinical trial to report on a topical gel for prevention of HIV acquisition among HIV-negative women, reported a 39% effectiveness in preventing HIV transmission. 62 The iPrex trial, also reported in 2010, reported a 44% effectiveness of daily oral pre-exposure prophylaxis (PrEP) in preventing HIV .

Categorical Spending - Project Listing - NIH Research ~ Quick access to statistics from the NIH Data Book and annual reports produced by the NIH OER’s Division of Information Services. . University of North Carolina Global HIV Prevention and Treatment Clinical Trials ERON, JOSEPH UNIV OF NORTH CAROLINA CHAPEL HILL . CAPRISA Clinical Trials Unit for AIDS/Tuberculosis Prevention and Treatment

Adherence in the CAPRISA 004 tenofovir gel microbicide trial ~ Although CAPRISA 004 was among the least-efficient HIV pre-exposure prophylaxis (PrEP) trials [22,23] for various reasons, with a major limitation in the field of adherence [24, 25], the case .

Quarraisha Abdool Karim / Columbia Public Health ~ Quarraisha Abdool Karim, PhD, Associate Scientific Director of CAPRISA, is an infectious diseases epidemiologist whose main research interests are in understanding the evolving HIV epidemic in South Africa; factors influencing acquisition of HIV infection in adolescent girls; and sustainable strategies to introduce antiretroviral therapy in resource-constrained settings.

Pharmacokinetics and Pharmacodynamics in HIV Prevention ~ Introduction. O ver the past 2 years, results from multiple clinical trials have been published evaluating the efficacy of different antiretroviral (ARV)-based strategies for the prevention of human immunodeficiency virus (HIV) transmission ().Unfortunately, results from these studies have been inconsistent. For example, 1% tenofovir (TFV) vaginal gel demonstrated a 39% reduction in HIV .